Doxoves® - PEGylated Liposomal Doxorubicin HCl
Doxorubicin HCl is loaded into PEGylated liposomes composed of HSPC/CHOL/mPEG2000-DSPE (56.2:38.5:5.3 mol/mol) with ammonium gradient by the active loading approach. It is comparable to the commercial product DOXIL®. The liposomes are prepared to very high quality with consistent lot-lot characteristics. Narrow particle size distribution and high drug encapsulation efficiency.Note the high drug concentration (4mg/mL compared to 2 mg/mL for DOXIL®) allows the researchers to perform experiments at higher concentration/doses.
Product For Research only and NOT for Human Use
Specifications
Product code: F30204B-D
Lipid composition: HSPC/CHOL/mPEG2000-DSPE (56.2:38.5:5.3 mol/mol)
Lipid concentration: 40.0 mM
Doxorubicin HCl: 4.0 mg/mL
Encapsulation efficiency: > 95% (typically 98%)
Loading battery: 250 mMammonium sulfate
Mean particle size: 85 nm (80 - 90 nm)
External solution: 10% sucrose, 10 mM histidine, pH 6.5
Shelf-life:6 months, storage:2-8 degree C
HSPC: hydrogenated phosphatidylcholine (Soy)
CHOL: cholesterol
mPEG2000-DSPE: 18:0 PEG2000 PE:1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
FormuMax常用产品报价单
产品名 | 货号 | 公司分类 | 商城分类 | 美金价 |
FormuMax/Alendrosome™ - Alendronate Liposomes (Neutral)/F70103A-N/ | F70103A-N | Clophosome® - Clodronate Liposomes | 细胞转染 | 599.00 | FormuMax/Combo kit of Doxoves® and plain control liposomes/2 mL/F30204C-D-2 | F30204C-D-2 | Doxoves® - Liposomal Doxorubicin HCl | 激素 | 619.00 | FormuMax/Combo kit of Doxoves® and plain control liposomes/10mL/F30204C-D-10 | F30204C-D-10 | Doxoves® - Liposomal Doxorubicin HCl | 抗荧光素 | 2159.00 | FormuMax/Combo kit of Doxoves® (2.0mg/mL) and plain control liposomes/2 mL/F30204C-D2-2 | F30204C-D2-2 | Doxoves® - Liposomal Doxorubicin HCl | 抗生物素 | 399.00 | FormuMax/Combo kit of Doxoves® (2.0mg/mL) and plain control liposomes/10mL/F30204C-D2-10 | F30204C-D2-10 | Doxoves® - Liposomal Doxorubicin HCl | 链霉亲和素结合物 | 1349.00 |