Clophosome®-A- Clodronate Liposomes (Anionic)
Clophosome®-A, negatively-charged clodronate liposomes, offers superior efficiency of macrophagedepletion. Clodronate molecules are encapsulated in LUV liposomes for superior activity, physical and chemical stability, and convenience of use. It is formulated to an exceptionally high clodronate/lipid ratio. Free clodronate is cleaned out and the liposomal encapsulation efficiency of clodronateis more than 90%.Clophosome liposomes remain homogenous even after long term storage in fridge. It is not viscous and easy to inject even with fine needles.It is manufactured sterilefor long term shelf-life.
The product is suitable for dosing with various routes includingintravenous, intraperitoneal, subcutaneous, intranasal,intratracheal and etc. We have achieved > 90%depletion in splenicmacrophages (red pulp macrophages) 24 hours after a single 0.2 mL intravenous injection.A starting dose of 0.15-2 mL (i.v. or i.p.) for 20-25ganimal body weight is recommended for good consistency in macrophage depletion. Optimization is recommended for specific applications.
Specifications
Product name: Clophosome®-A
Product code: F70101C-A
Active: clodronate disodium.CAS: 22560-50-5, 7 mg/mL
Lipid composition:phosphatidylglycerol,phosphatidylcholine and cholesterol
Bulk solution:phosphate buffered saline (20mMsodiumphosphate, 09wt% NaCl), pH 7.0-7.5
Shelf-life:6 monthsguaranteed for unopened vials at 2-8 degree C (guaranteed starting from the date of delivery, replacement only)
See sample CofA
FormuMax常用产品报价单
产品名 | 货号 | 公司分类 | 商城分类 | 美金价 |
FormuMax/Alendrosome™ - Alendronate Liposomes (Neutral)/F70103A-N/ | F70103A-N | Clophosome® - Clodronate Liposomes | 细胞转染 | 599.00 | FormuMax/Combo kit of Doxoves® and plain control liposomes/2 mL/F30204C-D-2 | F30204C-D-2 | Doxoves® - Liposomal Doxorubicin HCl | 激素 | 619.00 | FormuMax/Combo kit of Doxoves® and plain control liposomes/10mL/F30204C-D-10 | F30204C-D-10 | Doxoves® - Liposomal Doxorubicin HCl | 抗荧光素 | 2159.00 | FormuMax/Combo kit of Doxoves® (2.0mg/mL) and plain control liposomes/2 mL/F30204C-D2-2 | F30204C-D2-2 | Doxoves® - Liposomal Doxorubicin HCl | 抗生物素 | 399.00 | FormuMax/Combo kit of Doxoves® (2.0mg/mL) and plain control liposomes/10mL/F30204C-D2-10 | F30204C-D2-10 | Doxoves® - Liposomal Doxorubicin HCl | 链霉亲和素结合物 | 1349.00 |