DiO Labeled Fluorescent Control Liposomes for Clophosome^® -A (Anionnic)

Thefluorescent control liposomescontainthe green lipophilic dye DiO incorporated in the bilayers. It has comparable physical and chemical attributes as for the Clophosome^® except noactive is encapsulated inside. It is used for tracking the cellular uptake of the liposomes by common methods like confocal, FACS, etc.

Thegreen fluorescent, lipophilic carbocyanineDiOC18(3)is widely used as a lipophilic tracer. It is weakly fluorescent in water but highly fluorescent and quite photostable when incorporated into membranes. It has an extremely high extinction coefficient and short excited-state lifetimes (~1 nanosecond) in lipid environments.

Specifications

Lipid composition:phosphatidylcholine,phosphatidylglycerol andcholesterol

Dye: 0.15 mM (0.13mg/mL)

Stability: 6 months for unopened vials

Storage: 2-8 ºC

'DiO'; (Invitrogen D-275)DiOC18(3) (3,3'-Dioctadecyloxacarbocyanine Perchlorate)

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