Clophosome®-A-Clodronateliposomes(Anionic)
Clophosome®-A,negatively-chargedclodronateliposomes,offerssuperiorefficiencyofmacrophagedepletion.ClodronatemoleculesareencapsulatedinLUVliposomesforsuperioractivity,physicalandchemicalstABIlity,andconvenienceofuse.Itisformulatedtoanexceptionallyhighclodronate/lipidratio.FreeclodronateiscleanedoutandtheLiposomalencapsulationefficiencyofclodronateismorethan90%.Clophosomeliposomesremainhomogenousevenafterlongtermstorageinfridge.Itisnotviscousandeasytoinjectevenwithfineneedles.Itismanufacturedsterileforlongtermshelf-life.
Theproductissuitablefordosingwithvariousroutesincludingintravenous,intraperitoneal,subcutaneous,intranasal,intratrachealandetc.Wehaveachieved>90%depletioninsplenicmacrophages(redpulpmacrophages)24hoursafterasingle0.2mLintravenousinjection.Astartingdoseof0.15-2mL(i.v.ori.p.)for20-25ganimalbodyweightisrecommendedforgoodconsistencyinmacrophagedepletion.Optimizationisrecommendedforspecificapplications.
Specifications
Productname:Clophosome®-A
Productcode:F70101C-A
Active:clodronatedisodium.CAS:22560-50-5,7mg/mL
Lipidcomposition:phosphatidylglycerol,phosphatidylcholineandcholesterol
Bulksolution:phosphatebufferedsaline(20mMsodiumphosphate,09wt%NaCl),pH7.0-7.5
Shelf-life:6monthsguaranteedforunopenedvialsat2-8degreeC(guaranteedstartingfromthedateofdelivery,replacementonly)
SeesampleCofA
FormuMax常用产品报价单
产品名 | 货号 | 公司分类 | 商城分类 | 美金价 |
FormuMax/Alendrosome™ - Alendronate Liposomes (Neutral)/F70103A-N/ | F70103A-N | Clophosome® - Clodronate Liposomes | 细胞转染 | 599.00 | FormuMax/Combo kit of Doxoves® and plain control liposomes/2 mL/F30204C-D-2 | F30204C-D-2 | Doxoves® - Liposomal Doxorubicin HCl | 激素 | 619.00 | FormuMax/Combo kit of Doxoves® and plain control liposomes/10mL/F30204C-D-10 | F30204C-D-10 | Doxoves® - Liposomal Doxorubicin HCl | 抗荧光素 | 2159.00 | FormuMax/Combo kit of Doxoves® (2.0mg/mL) and plain control liposomes/2 mL/F30204C-D2-2 | F30204C-D2-2 | Doxoves® - Liposomal Doxorubicin HCl | 抗生物素 | 399.00 | FormuMax/Combo kit of Doxoves® (2.0mg/mL) and plain control liposomes/10mL/F30204C-D2-10 | F30204C-D2-10 | Doxoves® - Liposomal Doxorubicin HCl | 链霉亲和素结合物 | 1349.00 |